Views:67 Author:Site Editor Publish Time: 2019-08-06 Origin:Site
The cardiovascular system is one of the most important systems in the human body. Its function is to shoot blood from the heart to the artery and transport various substances to the tissue to achieve the body's metabolism. The blood ejection function of the heart depends on the integrity of myocardial electrical activity and mechanical contraction. Normal myocardial electrical activity and contractile force are in a relatively stable equilibrium state of excitatory and inhibitory activities, and are regulated and controlled by the cardiovascular system. This equilibrium state ensures the normal function of myocardial ejection. Some factors can invade certain parts of the system, destroy this equilibrium state, cause myocardial electrophysiological disorders, and make the system's regulation and control abnormal. Therefore, the method and purpose of treatment is to correct and adjust the abnormality of the system to return it to a normal state.
The activity of the heart is composed of myocardial electrophysiology and myocardial contractility. Normally, it is in a state of balance to meet the function of cardiac ejection when the heart is resting or in emergency. This steady state of the heart is regulated and suppressed by the heart itself and the nerve body fluid.
Certain factors will directly damage the electrophysiological and myocardial activities of the heart through various ways, so that the normal balance of the heart is destroyed, beyond the regulation range of the heart itself and the system, causing excessive excitability or excessive inhibition of the heart. Understanding these phenomena is of great significance for the diagnosis and treatment of cardiovascular diseases.
The electrophysiological activity of the heart is mainly manifested in the three aspects of self-discipline, excitability and conduction of the myocardium. When electrophysiological abnormalities occur, it can cause these three aspects abnormal, causing clinical arrhythmias.
Normal myocardial muscle can increase the strength of 5-7 times under stress, which is called the reserve function of the heart. Some disease states can cause this function to increase or decrease, which in turn causes abnormal cardiac function.
When cardiovascular disease occurs, it is often accompanied by an abnormality of autonomic nerve function regulation, which aggravates the abnormalities of myocardial electrophysiology and contractility.
It can be seen from the above that various factors can cause abnormalities in cardiac excitability and inhibition, which in turn cause abnormalities in cardiac function. The treatment of cardiovascular disease should be based on the use of inhibitory drugs in patients with excessive excitability of the heart, and the use of excitatory drugs in those with excessive inhibition to restore balance between the two, so that the pathological heart activity returns to normal.
Various tachyarrhythmia reflect the hyperexcitability or conduction abnormality of myocardial electrophysiology, which can be treated by inhibitory drugs or surgery. For various pre-systolic tachycardia and tremors, drugs that inhibit heart rate or conduction can be used to quickly reduce the rapid heart rate to a normal heart rate. For some arrhythmias such as supraventricular tachycardia, atrial fibrillation, ventricular tachycardia, etc., radiofrequency ablation or surgery can also be used to eliminate ectopic pacemakers or bypass and restore normal sinus rhythm and conduction pathways.
Various brady arrhythmias reflect a weakened or inhibitory increase in myocardial electrophysiological excitability. Surgical treatment with stimulant drugs or increasing heart rate can make the heart rate to normal, such as severe bradycardia, atrioventricular block and various escape rhythms using stimulation or improving sinus heart rate and strengthening the atrioventricular.
3.3.1 The enhancement of myocardial contractility, that is, the treatment of increased excitability. Diseases such as hypertrophic hypertrophic cardiomyopathy, rheumatic heart disease, etc., in the early stage of heart disease, manifested as compensatory enhancement of myocardial contractility, increasing myocardial oxygen consumption, while reserves weakening. Use a blocker that inhibits myocardial contractility, such as a B blocker. Calcium antagonists can inhibit excessive contraction of the myocardium and reduce myocardial oxygen consumption, thereby protecting the function of the heart.
3.3.2 The reduction of myocardial contractility, that is the treatment of inhibition. Some heart diseases such as dilated cardiomyopathy, myocarditis, etc., their damage sites are in the myocardium, when the myocardium is violated, the contractile force is significantly weakened, and the drugs that excite the myocardium, such as the ocean, are used. Rehmannia drugs can improve myocardial contractility and improve heart function.
According to the pathological changes of heart disease, different stages have different situations. Therefore, the treatment policy should also be changed. In the early stage of heart failure, clinical manifestations are increased heart rate, increased contractility and other excitability, so using drugs that inhibit the heart can inhibit this state; in the late stage of heart failure, clinical manifestations are heart rate slowing down and weakening of myocardial contractility. At this time, inhibitory drugs should not be used, but excitatory drugs should be used to improve heart rate and myocardial contractility and restore the heart's ejection function."
Taking the right methods and measures will help correct abnormal pathological changes. Then the cardiovascular system can change an unbalanced unstable state to a balance stable state, and the ejection function of the heart is restored.
People need to learn more about cardiovascular disease knowledge, including cardiovascular disease prevention and control, and pay attention to our own health.